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Stendra is a new anti-impotence medication. It belongs to a class of drugs called ‘PDE-5 inhibitors’. It is faster acting and is more selective than the other PDE-5 inhibitors. Avanafil is the active constituent present in Stendra. Avanafil, chemically, is a pyrimidine derivative and is only available as the S-enantiomer. The FDA approved this medication on April 27, 2012.

Stendra is prescribed to treat sexual dysfunction in males. Along with sexual arousal, it acts by improving the blood supply to the penile organ to help a man obtain and maintain an erection. As compared to other PDE5 inhibitors such as Sildenafil and Vardenafil, it is more selective for PDE5 enzyme. Stendra has the fastest absorption. The peak plasma concentration is achieved in about 30 to 45 minutes. About two-thirds of the users were able to indulge in sexual intercourse within 15 minutes.

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